Tuberin & Harmatin Research - Debbie Clements (Fellow)

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Tuberin & Harmatin / Hamartin Research - Debbie Clements (Fellow)

Post by siteadmin » Sun Jun 12, 2005 9:25 am

Debbie a fellow of the University of Nottingham Clinical Sciences.

Tuberin and Harmatin / hamartin interaction 'FRET'

Tuberin 'tag' dye identifier - Cyan Florecent Protein (CFP)
Harmatin / hamartin'tag' dye identifier - Yellow Florecent Protein (YFP)

Gene(s) associated to tuberous sclerosis (TSC) that encode the protein products hamartin /hamartin and tuberin, cause a mutation of the TSC gene(s), that leads to the development of the heritable disorder TSC.

This leads to a disorder and forms hamartomas in several organs in the body which has lead to the rapid spread of the lung disease called - lymphangioleiomyomatosis (LAM).

Research is on-going on how tuberin interaction in LAM affects LAM patients.

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